Personally I would not rate Empathy, Kindness or Love as the top Human traits. Probably bloody minded stubborness in the face of unbelievable suffering would be my pick.

Hair-splitting. My point was that transhumanism aims to keep positive traits while moving away from negative ones.

We agree the transhumanism in the real world is a philosophical movement, and the transhumanism as a sci-fi subgenre a different thing.

No, no it really isn't. There's plenty of transhumanist sci-fi that maintains the ideology that technology will improve the human condition. Star Trek for example, is transhumanist in many regards. Advancements in science and technology have largely allowed humanity to move away from their more "base" instincts into more higher-minded ways of life.

Cyberpunk is its own sci-fi sub-genre. And probably a more popular one.

The idea of scan a brain to copy all the memories and loading to a second body is too difficult in the real life, but we are talking about fantasy where you can change gender with only wear a cursed belt.

The answer to this question depends on if you want sci-fi(hard science fiction), sy-fi, sci-fy or sy-fy(strong "science" fantasy). Pathfinder/D&D is pure fantasy. Including Psionics or Starjammer makes it sy-fy.
Sy-Fy differs notably because almost all of the science is hand-waived away in favor of creating a fantasy narrative.
Sy-fiction does the same handwaiving when it comes to "science" but aims for a more believable "fiction" reality, usually in the very near future where *something something science* has created a dramatic change in the way humans live, but much of life is fundamentally the same.
Sci-Fy pays attention to the science, but aims for more fantastical results (Shadowrun is a good example), the science matters, but the result of the science is still fantasy.

The sci-fi doesn't talk only about the future technology, but how that could be used in the wrong way, for example to create new biological weapons. Do remember the (techno)virus Extremis in Iron Man's comics (not MCU). What if the medicine finds the secret of the eternal youth, and the government offers it to the citizens, but only who are "loyal"? A terrorist group could hack the healing nanobots by a target to cause the death.

That tends to be covered under the cyberpunk header. Technology, and the best laid plans of mice and men are in a cyberpunk approach, almost always going to go astray. OK, you are right, I don't mean really transhumanism, but brain uploading or mind transfer. Why not to be added to a d20 System if there are other games like Mindjammers or Eclipse Phase. Why not a Starfinder version of the 2013 videogame "Remember me"?

* What if a player wants surrogates, remote control androids? Like that movie with Bruce Willis, or James Cameron's avatar. Maybe some coward players would like to use in a space survival horror game.

IMO, in a hard sci-fi setting, the question is one of resources. You need a digital network capable of supporting a human mind, and then robot shells capable of being controled remotely. It's believable sci-fi assuming you set up the technology to be available.

If you're going to magic your way to the answer, then that's sy-fy, not sci-fi.

All I'm saying is you need to determine your approach before you can determine what you're including. Do people need high-tech gizmos and cool tech to accomplish this? Or do they need a magic spell?

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